About 40 years ago, when the first case of HIV was first discovered, it was seen as a death sentence because the cure was far fetched at that time.
Today, more advanced drugs that can effectively manage and control HIV have been developed. They have proven to be more effective, yielding high success rates, and posing even fewer and less serious side effects. Lopimune is a good example of one of these drugs. It is an antiretroviral agent designed to prevent the virus from replicating, thus reducing its count and eventually taking it below detectable levels. It contains the following ingredients: lopinavir (200 mg) and ritonavir (50 mg).
Lopimune was developed by Cipla, a reputable and award-winning pharmaceutical company known for manufacturing high-quality drugs. It has been approved by the United States Food and Drug Administration (FDA) for the treatment of HIV.
Benefits of Lopimune
While there are a lot of antiretroviral medications on the market, Lopimune stands out due to certain reasons, some of which include:
- milder side effects. As a recently developed drug, Lopimune poses a relatively low risk of side effects. This can be observed from the number of positive reviews from users compared with those from a few other products;
- availability. Lopimune is widely available. It can be gotten from walk-in stores as well as online stores;
- ease of administration.
Besides all of the above, this medicine is fairly affordable.
Mechanism of Action
A good way to get a good grasp of how this med works to effectively manage and control HIV is to first understand how it infects an individual.
When HIV makes contact with a host, it finds a way to cells and inserts its DNA in the DNA of the host’s cells. Once this is achieved, the virus continues the process, going on to infect other cells, increasing in number rapidly. As they grow in number and become stronger, they launch an attack on the host’s immune system, destroying it bit by bit, until it becomes completely weak and incapable of protecting the body against even the simplest diseases.
At this juncture, opportunistic infections easily attack and overrun the immune system, wreaking havoc gradually. Opportunistic infections are infections that take advantage of a weakened immune system to attack its host.
Combined, lopinavir and ritonavir reduce the viral load in an infected individual by preventing the virus from growing and infecting more cells. This way, the viral strength is at a minimum, giving room for the immune system to recuperate, become stronger and capable of fighting off diseases once more.
It is worthy of note that to achieve and maintain an undetectable viral load with this drug, the prescription must be strictly adhered to. Skipping doses can give the virus a chance to increase in count, become stronger and resistant to the drug.
Safe Dosage of Lopimune
Lopimune 200/50 mg tablet is the recommended dose for the control of HIV/AIDS. It should be taken before a meal or 2 hours after, as prescribed by a doctor. The tabs are not to be broken, chewed, or crushed, but swallowed whole.
This drug can be taken once or twice daily, depending on certain factors. For example, the once daily dose is not to be taken by pediatric patients. (babies that are 14 days and over). On the other hand, the twice daily dose is based on body weight and surface area.
The once daily dose is not recommended in the following cases:
- when the drug is used in combination with nevirapine, efavirenz, or nelfinavir;
- during pregnancy;
- carbamazepine, phenobarbital, or phenytoin.
Furthermore, adult patients with 3 or more Lopimune resistance-associated substitutions such as L33F, G48V, K20M/N/R, I84V, L10F/I/R/V, L24I, M36I, I54L/T/V, I47V, and V82A/C/F/S/T, are not to take the once daily dose. They must be given twice daily dosing. On the flip side, those with less than 3 resistance-associated substitutions can be given this dose.
This drug is only beneficial when it is used in combination with other antiretroviral meds. A doctor or healthcare provider can help you determine your combination.
Possible Lopimune Side Effects
Every drug posses side effects and Lopimune is not an exception. However, because its benefits far outweigh its downsides, it is approved for use. Negative after-effects of this drug may be mild or severe. Some mild negative after-effects of this med include:
- weight loss;
On the other hand, severe side effects may include:
- mood or mental changes;
- clinical depression;
- swollen glands in the neck;
- blurry vision;
- increased cholesterol levels in the blood.
While the above-listed mild side effects are common, they often go away within a short period of time. The severe side effects, on the other hand, are very rare and should be reported to a doctor immediately after they’re noticed.
This is not a complete list of the possible side effects of this drug. To get to know all possible side effects that may result from the use of Lopimune, refer to the label within the drug, or consult your pharmacist or doctor.
Interaction with Other Medications
Drugs interact differently, and the effects vary from one person to the other. When other drugs interact with Lopimune, their efficacy, as well as that of Lopimune, may be reduced. In fact, the side effects may change and could be fatal. Some of the substances this med can interact with include:
- medicine. Some meds which interact with Lopimune include: Atorvastatin, Carbamazepine, Fluoxetine, Erythromycin, Alprazolam, Acarbose, and Rosuvastatin, among others;
- alcohol. There is no known interaction with alcohol. However, intending users are advised to consult their doctor before commencing treatment with this med;
- diseases. Intending users who have any of the following diseases – diabetes, cardiovascular disease, and diabetes Mellitus, especially liver disease and hemophilia – should use this med with extreme care as it can increase the risk of side effects or worsening the condition;
- food. Presently, there is no known information regarding Lopimune’s interaction with food. However, fatty foods are better to be avoided when taking the drug, as it is known to slow down the effects of certain drugs.
In all, it is very important to check all possible interactions through the drug label or with a pharmacist before starting treatment.
Consumer Reviews and Ratings
Based on data gathered from reliable online pharmacies that sell Lopimune, there are positive as well as negative reports made about the drug. However, the positive reports made far exceeded the negative ones. Those who spoke in favor of the drug laid emphasis on ease of administration, availability, pocket-friendly cost, and most of all, its mild side effects.
On the flip side, a few users complained about experiencing side effects such as dizziness and upset stomach, which they found very discomforting. While some of them indicated their plan to discontinue treatment with the drug, others stated their plan to continue with the drug after a consultation with their healthcare provider, as they feared that the source of the side effects was due to an interaction.
In a nutshell, based on the ratio of positive reviews to the negatives, this med has been proven to have high tolerability. In this light, with correct usage, and strict adherence to prescription, the chances of experiencing any severe side effects are low.
How to Buy Lopimune Tablets for Cheap Price Online?
Lopimune is no doubt a highly effective treatment for HIV/AIDS if used as a part of therapy. Though its price is relatively affordable, it can be bought even cheaper. However, this is dependent on where you buy it and how. It is available in walk-in stores as well as online pharmacies.
While buying online or on sale is cheaper most of the time, it’s advised to buy from verified stores with a history of quality services. This is to ensure that genuine tablets that will be effective are bought. BuyPrEPOnline is an online pharmacy that sells Lopimune as well as other anti-HIV drugs at a really affordable price. We’ve got lots of experiences shared from users of these meds, so those intending buyers can determine if they’re making a good choice.
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